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Activation of the proto oncogene c
2018-11-09
Activation of the proto-oncogene c-myc is associated with cellular growth and proliferation programs (Dang, 2013) and is therefore an important feature of cancer initiation and maintenance (Gabay et al., 2014). Furthermore, c-myc induces the expression of telomerase reverse transcriptase (TERT) and
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br Materials and Methods br Results br Discussion
2018-11-09
Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s
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br HEV Mutations and Vaccination Prevention of HEV
2018-11-09
HEV Mutations and Vaccination Prevention of HEV infection in endemic areas is based on the implementation of appropriate hygiene and sanitary measures to avoid fecal-oral transmission. In regions where HEV infection is sporadic, the consumption of raw food should be avoided. HEV infection can be
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Among the participants in our
2018-11-09
Among the 1303 participants in our study, 74% (n=964) reported xerostomia (Table 2). Xerostomia prevalence was highest among SS participants (87.4%, 95% CI: 84.8%–89.8%) followed by Sicca participants (72.4%, 95% CI: 67.4%–77.0%) and the ISS group (38.1%, 95% CI: 32.0%–44.4%). The absolute differenc
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br Materials and Methods br Results br
2018-11-09
Materials and Methods Results Conclusion Our meta-analysis suggested that DNMT1 rs16999593 and DNMT3A rs1550117 could contribute to GC and that DNMT3B rs1569686 might function as a protective factor against gastric carcinogenesis. By using these significant SNPs as biomarkers, it is feasibl
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The electronic nose was also used to
2018-11-09
The electronic nose was also used to measure the shrimp freshness [18–22], the result showed that the electronic nose could detect the odor change of shrimp. Most application of electronic nose focused on pattern recognition techniques [19–26]. Principal component analysis (PCA) was a pattern recogn
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br Conflict of interest br Acknowledgments
2018-11-09
Conflict of interest Acknowledgments Authors greatly acknowledge Misses N. Watanabe and A. Misao for their helps in experiments. This work was financially supported by Grant-in-Aid for Scientific and Research (B) (No. 21350045 and No. 2541049) from the Ministry of Education, Culture, Sports, S
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Sin embargo no han cambiado las cosas con
2018-11-09
Sin embargo, ¿no han cambiado las cosas con la “Nueva Geografía Económica” que según su representante más conocido, Paul Krugman (1998, 7), “serves the important purpose of placing geographical analysis squarely in the economic mainstream”? Los geógrafos, por lo menos, se muestran poco convencidos.
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Visto as el libro que consta de cap
2018-11-09
Visto así, el libro, que consta de 25 capítulos, en realidad podría dividirse, según mi apreciación, en tres partes: la primera, los años de formación de , desde que decidió purchase ryanodine incorporarse a la revolución por su propia voluntad y tratando de ocultarlo a su madre, hasta su arribo a l
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Caspase-3/7 Inhibitor manufacturer Las ensambladoras gobiern
2018-11-09
Las ensambladoras gobiernan la cadena con respecto a los proveedores y establece los estándares de desempeño con respecto a costo, calidad, tiempo de entrega, emisiones, reciclaje, etcétera. Para lograr la competitividad sistémica en la cadena se espera que aquellos que gobiernan promuevan el aprend
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br Methods br Results br Discussion Persistence
2018-11-09
Methods Results Discussion Persistence of hyper-invasive strain types containing PorA:FetA:clonal complex associations have been described with ST-32 isolates predominantly associated with the antigenic profiles P1.7,16:F3-3 and P1.19,15:F5-1 as found here (Watkins and Maiden, 2012). Data p
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Furthermore the inhibitor binding can also be altered by
2018-11-09
Furthermore, the inhibitor binding can also be altered by various mutations. Prime examples are acquired intrinsic resistance mutations that have marred the success of tyrosine kinase inhibitors (TKIs) such as gefitinib, erlotinib and imanitib, prompting efforts for second- and third-line treatments
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Previous work on a limited scale compared to
2018-11-09
Previous work, on a limited scale compared to Yu et al.\'s, has also sought to explore the mutational spectrum of lung cancer tissues in Xuanwei. A small exploratory study among 40 never smoking females who had NSCLCs from Xuanwei had mutations detected in 35% of tumors (). mutations were observed
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br Introduction The Middle East respiratory syndrome coronav
2018-11-09
Introduction The Middle East respiratory syndrome coronavirus (MERS-CoV) is the only lineage C betacoronavirus known to infect humans (Annan et al., 2013; Anthony et al., 2013; van Boheemen et al., 2012). Similarly to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV infection ca
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AZD1152 Sigma receptors are arguably the most
2018-11-09
Sigma receptors are arguably the most mysterious signaling proteins. While the S1R was mischaracterized as an opioid receptor (Martin et al., 1976) until its gene sequence became available (Hanner et al., 1996), the S2R has evaded many attempts to decipher its genetic coding. For example, mass spect
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