• br Results br Discussion Insertion of reporter cassettes int

  2018-10-26

  

  Results Discussion Insertion of reporter cassettes into the Lgr5 locus has enabled characterization of mouse ISCs (Barker et al., 2007, 2010) and development of ex vivo organoid culture systems (Sato et al., 2009). Subsequent transplantation assays using fetal or adult ISCs have paved the way

• Human pluripotent stem cells hPSCs including

  2018-10-26

  

  Human pluripotent stem over here (hPSCs), including human embryonic stem cells (Thomson et al., 1998) and induced pluripotent stem cells (iPSCs) (Takahashi et al., 2007), provide an ideal in vitro model to recapitulate human hematopoietic development. We have shown that hPSC-derived HSC-like cells p

• We previously identified a role for

  2018-10-26

  

  We previously identified a role for the transcription factor Gata3 in prostate cancer (Nguyen et al., 2013). GATA3 expression is lost during cancer progression in both mouse and human prostates. In Pten-deficient mice, acute inactivation of Gata3 accelerates prostate cancer progression, while its su

• lysophosphatidic acid The electrical properties of cells wer

  2018-10-26

  

  The electrical properties of lysophosphatidic acid were recently analyzed by EIS during the differentiation of stem cells (Angstmann et al., 2011; Bagnaninchi and Drummond, 2011; Venkatanarayanan et al., 2013). These pioneering works have demonstrated a possibility of using changes in impedance as

• Study of microglia has been largely restricted to non

  2018-10-26

  

  Study of microglia has been largely restricted to non-human models (mostly mouse), since availability of fresh primary human microglia is very limited and they cannot be propagated. Moreover, microglia rapidly lose their unique identity when removed from the inos inhibitor environment and cultured

• their mathematical expectations follow the expressions br

  2018-10-26

  

  their mathematical expectations follow the expressions According to the CLT for independent random variables , for N → ∞  the expression tends to a standardized Gaussian random variable. Therefore for N ≫ 1 we have the following approximate equalities: where θ0, , are the standardized Gaussian

• br Introduction Light emitting diodes

  2018-10-26

  

  Introduction Light emitting diodes (LEDs) due to their technical and economic advantages (low power consumption, a long service life and low service costs, a small size, the absence of hazardous IR and UV radiation, ease of disposal) are the leading contenders for future light sources. Currently,

• br Explaining health inequalities Three main theories have b

  2018-10-26

  

  Explaining health inequalities Three main theories have been documented to account for health inequalities: materialist, psychosocial, and behavioural/cultural (Bartley, 2008). Methods The ‘Local Health Inequalities in an Age of Austerity: The Stockton-on-Tees Study’ is a mixed method, interd

• br Conflicts of interest br Acknowledgements

  2018-10-26

  

  Conflicts of interest Acknowledgements The authors are grateful for the fieldwork data collection undertaken by student and assistants from the Faculties of Environmental Design (Karina Lamy), Medicine (Lindsay Burton, Ann Toohey, Monica Viapiana), Science (Stefano Liccioli and Sarah Gingerick

• Greater access to fast food chains translates

  2018-10-26

  

  Greater access to fast food chains translates into an environment with increased opportunities to purchase and consume such items (Brug, 2008; Thornton, Bentley & Kavanagh, 2009). As governments at the Federal, state, and local levels strive to find new ways to improve enba health outcomes, a growi

• Additional models were tested to assess

  2018-10-26

  

  Additional models were tested to assess the robustness of the main results to the different specifications. These included whether having a history of bankruptcy prior to the age 40-health module influenced the overall results. None of the 370 women with a pre-40 health bankruptcy who were added, ho

• By contrast population strategies focus on universal strateg

  2018-10-26

  

  By contrast, arginase inhibitor strategies focus on universal strategies that affect all individuals, regardless of baseline risk of developing disease. This universality also has advantages and disadvantages. A population strategy typically seeks to decrease population-level risk of disease, which

• Many authors agree that information

  2018-10-26

  

  Many authors agree that aldose reductase inhibitors information technology (IT), and mostly the Internet, have become one of the most important tools for conducting international business and marketing activities (Sinkovics, Sinkovics, & Jean, 2013). In particular, IT-based capabilities have been f

• Yet the emphasis on the social and or

  2018-10-26

  

  Yet, the emphasis on the social and/or political purpose of timebanking may have obscured the fact that they are, at the core, exchange networks. TBs are created to offer a space for exchanges of services between individuals, even though the TB may encourage other activities, such as social gatherin

• Other sensitivity and resolution analysis operations based o

  2018-10-26

  

  Other sensitivity and resolution analysis operations based on kernel values may as well read in the kernel files, do their analyses and produce output in the ASKI directories, according to the needs of the user (Fig. 2, ). ASKI additionally provides executables for minor auxiliary operations, e.g. t

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