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Chemotherapy is generally applied for metastatic diseases an
2018-10-22
Chemotherapy is generally applied for metastatic diseases and unresectable tumors. However, the role of chemotherapy in the treatment of MFH is not entirely clear. Several clinical trials incorporating the chemotherapy drug doxorubicin have demonstrated trends toward improved event-free survival wit
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Introduction Malignant fibrous histiocytoma MFH is a
2018-10-22
Introduction Malignant fibrous histiocytoma (MFH) is a pleomorphic sarcoma originally described by Ozzello et al in 1963 and O\'Brien and Stout in 1964. It is one of the most common soft-tissue sarcomas among adults, with a peak incidence between 60 and 70 years of age. It has been determined to ex
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In the reactive or pseudoepitheliomatous hyperplasia margins
2018-10-22
In the reactive or pseudoepitheliomatous hyperplasia, margins of the proliferating epidermis are often pointed or irregular rather than bulbous, with a more marked inflammatory infiltrate than a mild-to-moderate one, which is associated with carcinoma cuniculatum. In addition, the presence of anapla
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gap27 In recent years researches on
2018-10-22
In recent years, researches on anthocyanins have attracted more and more attentions, especially their isolation and purification [13–15]. In contrast, there have been few studies focusing on chemical structures and antioxidant activity of anthocyanins in edible rose. Therefore, the aim of this study
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Therefore the objective of the present study was to further
2018-10-22
Therefore, the objective of the present study was to further evaluate the effect of the 70% hydromethanolic extract of D. alata underground tuber for modulating TH1 (IL-2 and IFN-γ) and TH2 (IL-4 and IL-10) cytokine expression and its effect on the proliferation pattern of murine splenic T-lymphocyt
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Lai et al investigated the inhibitory effects
2018-10-22
Lai et al. [52] investigated the inhibitory effects of xanthigen, fucoxanthin, and punicic Ramelteon (70% in pomegranate seed oil) on the differentiation of 3T3-L1 preadipocytes. Xanthigen potently and dose-dependently suppressed accumulation of lipid droplets in adipocytes compared to its individua
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Introduction Alzheimer s disease AD is a chronic neurodegene
2018-10-22
Introduction Alzheimer’s disease (AD) is a chronic neurodegenerative disease and the most common cause of dementia, accounting for over 50% of individuals affected [1]. This disease is characterized by progressive memory impairment and cognitive decline interfering with daily life activities. The m
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ATPases play a significant role
2018-10-22
ATPases play a significant role in the contraction and relaxation cycles of the verbascoside by maintaining normal ion levels within the myocyte. Several factors are known to alter the activities of ATPases especially lipid peroxidation and membrane fluidity. It has been reported that isoproterenol
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Introduction Alzheimer s disease AD is a chronic neurodegene
2018-10-22
Introduction Alzheimer’s disease (AD) is a chronic neurodegenerative disease and the most common cause of dementia, accounting for over 50% of individuals affected [1]. This disease is characterized by progressive memory impairment and cognitive decline interfering with daily life activities. The m
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br Materials and methods br Statistical analyses
2018-10-22
Materials and methods Statistical analyses Results were expressed as mean±SEM (standard error of mean). Multiple group comparisons were performed by one-way analyses of variance (ANOVA) followed by the Bonferroni procedure for comparison of means. Comparisons between two groups were performed
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The objective of this work was to
2018-10-22
The objective of this work was to investigate if a synergistic coculture system of MSCs with endothelial sr9009 could affect the number and state of differentiation of harvested MSCs. In contrast to other papers, in this cell-cell communication topic, the investigation was carried out for a longer
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As expected PA could decrease the viability of NSCs
2018-10-22
As expected, PA could decrease the viability of NSCs in a dose- and time-dependent manner. In addition to its adverse effects on cell morphology, our speculation that PA might also be involved in apoptosis of NSCs was confirmed by TUNEL assay. Very interestingly, the effects of PA on apoptosis of NS
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The goals of the current study were to investigate
2018-10-22
The goals of the current study were to investigate the changes in anal sphincter pressure after IV or IM injection of MSCs in our previously established animal models. Our models (Salcedo et al., 2010; Zutshi et al., 2009a) allow measurement of anal sphincter pressure and EMG in vivo in a repeated,
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To identify a molecular marker that can
2018-10-22
To identify a molecular marker that can serve as an indicator of the differentiaion potential of the cell lines tested, we analyzed the p2x receptors levels of a group of genes in hESCs that include pluripotent transcription factors, modulators of various signaling pathways known to be involved in
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In order to enhance osteochondral commitment
2018-10-22
In order to enhance osteochondral commitment, we performed chondrogenic pre-induction of ATSC/β-TCP constructs. Ectopic bone formation was installed in more than 75% of samples, suggesting that a sufficient degree of determination was reached to obtain about as much new bone as with non-induced BMSC
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