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It is well known that TCDD is the
2024-07-16
It is well-known that TCDD is the most potent ligand of AhR and it regulates gene expression, such as CYP1A1, via activation of AhR (Mimura and Fujii-Kuriyama, 2003). Besides Tomblin et al. (2016) have recently shown that TCDD via AhR regulated L-type amino rna polymerase transporter 1 expression i
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In addition to plasma membrane
2024-07-16
In addition to plasma membrane sites, OCT3 was also observed associated with endomembranes, including mitochondrial membranes, with particularly strong expression in the outer nuclear membranes of both neurons and astrocytes (Gasser et al., 2017), indicating that, in addition to regulating extracell
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To further clarify the vascular cell types expressing AR sub
2024-07-16
To further clarify the vascular cell types expressing AR subtypes, double immunofluorescence staining for ARs and vascular endothelial 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium salt australia or vascular smooth muscles was performed. As shown in Fig. 3, Fig. 4, overlay images show the expre
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br ABCA and cancer drug response
2024-07-16
ABCA2 and cancer drug response Overall, the expression of ABC transporters has been linked with multidrug resistance phenotypes through the efflux of drugs via ATP-dependent transport. For example, 13 distinct transporters (ABCA2, ABCB1, ABCB4, ABCB11, ABCC1–6 ABCC10, ABCC11 and ABCG2) have been
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br Adiponectin in prostate cancer PC was documented
2024-07-16
Adiponectin in prostate cancer PC was documented as the leading type of malignancy in males in the US with respect to both the estimated number of cases (22,800) and deaths (27,540) (Siegel et al., 2016). Studies have reported an association between low APN levels and the progression of PC (Micha
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Introduction Adenosine monophosphate cAMP is
2024-07-16
Introduction Adenosine 3′,5′-monophosphate (cAMP) is a general-purpose signaling molecule present in most branches of life. Intracellular cAMP levels control diverse cellular functions. In bacteria, cAMP regulates metabolism by activation of the catabolite activator protein (CAP), also known as cAM
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br Results br Discussion Utilizing a
2024-07-16
Results Discussion Utilizing a proteomic approach, we identified HSP90β as a protein that becomes associated with surface AChR in agrin-stimulated muscle cells. We demonstrate that HSP90β does not interact with the AChR directly; instead, via direct interaction with rapsyn, HSP90β becomes asso
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The reductase family is composed of
2024-07-16
The 5α-reductase family is composed of three known isozymes, with the types I and II being the most known. Type I isozyme, which is the dominant form, can be found in the skin, liver, kidney, brain and lung. Furthermore, it has been evidenced that type I activity is several times higher in PC than i
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The compounds containing beryllium act as
2024-07-16
The compounds containing beryllium act as strong Lewis acids because of electron deficiency of the Be Auranofin []. Interactions of X-Be-Y compounds with different Lewis bases have been studied by Yanez and co-workers [], extensively. Recently, they proposed a class of extremely strong bidentate Be-
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2 nbdg br Experimental Section br Results and Discussion br
2024-07-16
Experimental Section Results and Discussion Conclusions The advantages of the novel enzymo-chemical method for Mn and Co assay are simplicity of analytical procedure and economic effect due to the usage of only one enzyme in the form of apo-enzyme. An effectiveness of the apo-arginase-based
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Introduction The corpus luteum CL is a transient
2024-07-16
Introduction The corpus luteum (CL) is a transient endocrine gland that differentiates from the thecal and granulosal cells of the ovarian follicle after ovulation. Its formation and limited lifespan in the mammalian ovary is important for fertility, as the CL produces progesterone (P4), the essent
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br Introduction Breast cancer is the
2024-07-15
Introduction Breast cancer is the second most lethal cancer among women, accounting for approximately 40,000 deaths in the United States in 2015 [1]. The prognosis of breast cancer has improved significantly with the identification of immunohistochemical subtypes that predict response to therapy
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Our results lead to the discovery and characterization of Vv
2024-07-15
Our results lead to the discovery and characterization of VvAAT2, a gene potentially involved in acetate accumulation in grape berries discovered through amino-acid feeding experiments. Incubation with exogenous amino acids has also been a key in the discovery of new genes affecting fruit aromas [13
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The study by Lo http www apexbt com
2024-07-15
The study by Lowry et al. (2001) pointed toward functionally uncharacterized DA- and 5-HT-accumulating neurons within the DMH as a potential target for rapid nongenomic effects of CORT. Similar DA- and 5-HT-accumulating systems are distributed throughout the central and peripheral nervous systems, s
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This study revealed that EAAT
2024-07-15
This study revealed that EAAT2 neuroscience peptides was increased 4–8 weeks after cauterization as our previous work (Park et al., 2009). RGC death could not be blocked despite activation of EAAT2, which is one of glutamate transporters in cone photoreceptors and some bipolar cells, in chronic ocu
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