• br Ultrasonic pretreatment of substrates Substrate

  2020-06-23

  

  Ultrasonic pretreatment of substrates Substrate pretreatment is widely used in the biofuel, textile and food industries since the substrates are always difficult to degrade. During some enzymatic hydrolysis reactions, the protective layer of the substrate impedes the reaction. Ultrasonic treatmen

• CSN was initially identified based on the constitutitvely ph

  2020-06-23

  

  CSN was initially identified based on the constitutitvely photormophogenic (cop) mutants from Arabidopsis thaliana [48]. csn mutants are Cullin deneddylation-deficient, consequently accumulate neddylated Cullins, and arrest growth shortly after germination [49, 50, 51]. Weak csn mutants have defects

• br Conflicts of interest br Financial

  2020-06-23

  

  Conflicts of interest Financial support NZ is an Established Investigator of the Dutch Heart Foundation (2013T111) and is supported by an ERC Consolidator grant (617376) from the European Research Council and by a Vici grant from the Netherlands Organization for Scientific Research (NWO; 91818

• br Methods br Results br Discussion Preclinical data

  2020-06-23

  

  Methods Results Discussion Preclinical data indicate that nepicastat modulates sympathetic drive to the calcitonin receptor with a mild pressor effect in various animal models of hypertension (Stanney et al., 1998). However in this clinical study, the doses of nepicastat employed did not s

• Luciferase Reporter Assay Kit Recent studies have shown arse

  2020-06-23

  

  Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma Luciferase Reporter Assay Kit [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of it

• The goal of this paper is to investigate the penalized

  2020-06-23

  

  The goal of this PF-03084014 paper is to investigate the penalized empirical likelihood method for the Cox model, as a competitor to the penalized partial likelihood. Since empirical likelihood (EL) was proposed by Owen, 1988, Owen, 2001, empirical likelihood methods have been investigated well from

• The study reported here had

  2020-06-22

  

  The study reported here had the primary goal to compare the methylation of HPV late genes with methylation of the DAPK promoter, and with histological or cytological diagnoses among high-risk patients that were referred to a colposcopy clinic based on abnormal cervical cytology. Based on the literat

• pain and inflammation Constitutive activity of Ras Raf MEK E

  2020-06-22

  

  Constitutive activity of Ras/Raf/MEK/ERK pathway plays a critical role on melanoma growth, thus inhibition of activity of Ras, Raf and MEK can reduce ERK activity, leading to a decrease in melanoma cell proliferation, survival and invasion (Burotto et al., 2014; Paluncic et al., 2016). Our results a

• The same reservoir of genes is involved in

  2020-06-22

  

  The same reservoir of Fomepizole sale is involved in fusions in all types of cancers, which predominantly encode kinases and transcriptional factors [102]. This makes fusion genes potential pan-cancer targets, and renders tumor categorization based on genetic profiling therapeutically reasonable. F

• Mitophagy is a selective autophagic process

  2020-06-22

  

  Mitophagy is a selective autophagic process which leads to the degradation of damaged mitochondria in response to metabolic or environmental stress conditions. In this study, we found that LFS-01 treatment significantly enhances p62 in a time-dependent manner. We found that the upregulation of p62 i

• br Experimental protocols br Acknowledgements This research

  2020-06-22

  

  Experimental protocols Acknowledgements This research was funded by the Croatian Ministry of Science, Education and Sports (Programmes 098-0982915-2948 and 098-0982522-2525), the Austrian Science Fund FWF (DK-MCD W1226, SFB LIPOTOX F30, P22832), and the Croatian-Austrian Intergovernmental S&T

• E is a classical initiator protein and as such plays

  2020-06-22

  

  E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral CTPB receptor known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to date, the m

• Calcipotriol Ginsenoside Re lysine mixture had increased ant

  2020-06-22

  

  Ginsenoside Re-lysine mixture had increased anticancer effects upon heat processing by regulating Bcl-2 and Bax (Yamabe et al., 2013). Ginsenoside Re (20mg/kg) inhibited NF-κB activation by inhibiting LPS binding to TLR4 on macrophages in TNBS-treated mice (Lee, Hyam, Jang, Han, & Kim, 2012). The ch

• GLP signaling mediates important renal functions as suggeste

  2020-06-22

  

  GLP-1 signaling mediates important renal functions [101], as suggested by the expression of both DPP-4 and GLP-1R in the kidney of several species, including humans [102]. However, controversial data exists on the specific expression pattern of these proteins, based on the specificity and sensitivit

• Amphiphilic compounds lower interfacial tension and

  2020-06-22

  

  Amphiphilic compounds lower interfacial tension and its biological production often results in a competitive environmental advantage (Darvishi et al., 2011). The reduction of interfacial tension can increase the biologically available surface areas resulting in increased metabolism of insoluble comp

15138 records 762/1010 page Previous Next First page 上5页 761762763764765 下5页 Last page