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Furthermore an observational cross sectional case control st
2019-05-29
Furthermore, an observational, cross-sectional case-control study used by the authors of 976 children aged 6–10 years, from an area of small towns immersed in the countryside in central Italy, estimated the rate of FAS as between 4 per 1000 and 12 per 1000 people in 2011. These rates cannot in any c
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br Methods br Results br
2019-05-29
Methods Results Discussion Conclusion Conflict of interest Introduction Placement of the left ventricular (LV) pacing lead in a tributary of the coronary sinus (CS) is one of the most challenging technical aspects of cardiac resynchronization therapy (CRT) device implantation. Fail
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On the other hand it was also shown
2019-05-29
On the other hand, it was also shown that multi-fraction long-course radiotherapy results in better re-calcification and fewer recurrences of spinal cord fluorescent probes within the irradiated spinal region [24,25]. In case of recurrence, Nieder et al. [10] reviewed that re-irradiation of the spi
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A number of studies have shown that zoledronic
2019-05-29
A number of studies have shown that zoledronic enolase has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was shown to r
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opioid receptor It is established that hypoxia
2019-05-29
It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 opioid receptor after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections also ind
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The TP related complications are given in Table Pericardial
2019-05-29
The TP-related complications are given in Table 3. Pericardial effusion without tamponade was seen in 2 patients (5.9%) in the TEE-guided TP group and 5 (8.8%) in the fluoroscopy-guided group. There was no pericardial tamponade in the TEE-guided group and only one patient experienced tamponade in th
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In addition evidence of similar resting HR
2019-05-29
In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy
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br Genetic basis for atrial
2019-05-29
Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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Stroke is second only to ischaemic heart disease as the
2019-05-29
Stroke is second only to ischaemic purchase Biotin-HPDP disease as the leading cause of death worldwide; one in six people will have a stroke in their lifetime. , on October 29, reminds us of these striking facts and the need for individuals to know the risk factors. Although the main risk factors
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In order to treat metastatic bone disease effectively
2019-05-28
In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu
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Ablation of a left sided accessory pathway
2019-05-28
Ablation of a left-sided accessory pathway requires delivery of RF current to the tissue near the mitral valve annular ring. These lesions may potentially cause mitral injury. Sometimes a trapped leaflet or chordae underneath the tip of the catheter may cause the insufficiency [7,8,12–14]. However,
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lck inhibitor In the days before Christmas adverse weather c
2019-05-28
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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First Speakman and colleagues do not mention the development
2019-05-28
First, Speakman and colleagues do not mention the developments in the 2000s, when notable EU attention was given to global health. In 2010, there was a high-level conference and the launch of a European Commission Communication, which stated that the EU\'s commitment to global health should mainly f
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Programmed death ligand PD L expression is
2019-05-28
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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br Discussion The presence of metastases
2019-05-28
Discussion The presence of metastases at the time of diagnosis is a significant prognostic factor in osteosarcoma [14]. Skeletal metastases at time of presentations appears to carry a worse prognosis than pulmonary metastases [15]. Furthermore, the chance of survival can be improved by surgical r
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