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Androgen signaling is central to prostate cancer
2018-11-14
Androgen signaling is central to prostate cancer development and progression. A milestone in progression of advanced prostate cancer when it transitions from endocrine-driven to paracrine- or intracrine-driven androgen signaling, with progressive complexities in steroid hormone biosynthesis and alte
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Several studies provide evidence of potential
2018-11-14
Several studies provide evidence of potential genetic contribution towards AAV (Knight et al., 2008, Monach and Merkel, 2010). The most convincing association has been with the major histocompatibility complex (MHC), especially the locus HLA DPB1*0401 (Wieczorek et al., 2010, Jagiello et al., 2004).
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C a IL and fMLP
2018-11-14
C5a, IL-8, and fMLP induced the SCR7 of CD11b and CD162 on the neutrophil surface and shed off CD62L, as detected by FACS (Fig. S6). HRG did not influence the basal and agonist-induced changes in adhesion molecules on the neutrophil surface except for activated form of CD11b (Fig. S6). Since HRG di
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br Conflict of Interest Disclosures br Author contributions
2018-11-14
Conflict of Interest Disclosures Author contributions Introduction Large for gestational age (LGA), defined as a birth weight≥90th percentile for gestational age, is the predominant adverse outcome associated with maternal hyperglycemia (Langer et al., 2005; Metzger et al., 2008). LGA is th
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One of the questions that arise from
2018-11-14
One of the questions that arise from the study is: What is the underlying cause for the rest of cases? As authors address in the paper, WES may not detect those variants in non-coding regions neither deletions nor gene rearrangements. Indeed, next-generation sequencing techniques using densely place
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Consistent with the sporadic reports in China characterizati
2018-11-14
Consistent with the sporadic reports in China, characterization of the blaKPC-2- and blaNDM-bearing plasmids recovered from CRE in this study indicated that IncX3 conjugative plasmids carrying blaNDM is the major gene involved in dissemination of blaNDM among clinical CRE strains (Yang et al., 2014,
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br Experimental design materials and
2018-11-14
Experimental design, materials and methods (http://www.mat.uniroma2.it/~gandola/ACQU/→ACQUA_Matlab_libraries.rar). Download http://www.mat.uniroma2.it/~gandola/ACQUA/→ACQUA_Matlab_libraries.rar. Acknowledgments M.A. acknowledges FRIAS COFUND Fellowship Programme (University of Freiburg,
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br Brain signatures of increased reward sensitivity and
2018-11-14
Brain signatures of increased reward sensitivity and reduced cognitive control in youth with behavior problems As mentioned previously, developmental differences in VS recruitment by rewards during fMRI have been interpreted as reflecting underlying development of DA activity in the mesolimbic sy
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The application of this same paradigm to
2018-11-14
The application of this GSK503 same paradigm to children revealed that attention\'s effect on response variability increases with age (Strait et al., 2014a), from ages three to 35, and may provide an objective index of the development of selective attention and inhibitory control. The development of
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br Conflict of interest br Acknowledgments This study
2018-11-13
Conflict of interest Acknowledgments This study was funded by the UK Medical Research Council (MRC) (G0802226) and the Behavioural and Clinical Neuroscience Institute (BCNI) at the University of Cambridge (jointly funded by the MRC and Wellcome Trust). Additional support was given by the Natio
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In sum understanding more precisely how mindsets relate
2018-11-13
In sum, understanding more precisely how mindsets relate to the processes that occur immediately after mistakes in this Exendin-3 (9-39) amide younger age range may open novel avenues for research and intervention to improve resilience. Thus, in the current study, school-age children performed a dev
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In the analysis of the structural
2018-11-13
In the analysis of the structural MRI data it was found that subjects with higher grey matter volume in the right parietal all trans retinoic acid benefitted more from the WMT than subjects in the same training group with lower grey matter volume (p=0.005), although this association did not survive
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La Conferencia de logr una asistencia
2018-11-13
La Conferencia de 1995 logró una asistencia sin precedentes: 17,000 participantes en la reunión oficial, con presencia relevante de delegaciones oficiales inclusivas de los diferentes poderes del Estado y la sociedad civil, práctica positiva que se ha expandido AVE 0991 otros foros de las Naciones U
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Esa escritura que llamamos propia y
2018-11-13
Esa escritura que llamamos propia y amarga, ¿no concibe la homosexualidad como algo ajeno?, ¿podría entenderla de otra manera si BAY 87-2243 tanta atención y agresividad, si produce interés e indiferencia? No lo creo. La única forma de escribir sobre lo o sobre uno mismo desde ese lugar subalterno e
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Bedtime and wake time were not related
2018-11-13
Bedtime and wake time were not related to overweight or obesity in our study, however an EL sleep timing behavior, corresponding to a longer duration of sleep, resulted in a better weight control compared to the others sleep timing behaviors. In a recent Australian cross-sectional study, adolescent
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