• Introduction Suicide is the leading cause of

  2018-10-24

  

  Introduction Suicide is the leading cause of death among young people in Australia, accounting for 25% of all deaths in the age groups 15–30 years (ABS, 2012). Non-fatal suicidal behaviours are also particularly prevalent among young people (Martin, Swannell, Hazell, Harrison, & Taylor, 2010). A nu

• br Ethical approval br Introduction The presence

  2018-10-24

  

  Ethical approval Introduction The presence of metal ions in the environment is of major concern due to their toxicity to many life forms. Unlike organic pollutants, the majority of which are susceptible to biological degradation, metal ions do not degrade into harmless end-products. The metals

• br Developing a model for Brazil

  2018-10-23

  

  Developing a model for Brazil In this section, we use the King and Fullerton methodology to find the expressions for the real required pre-tax rate of return “p” on Brazilian domestic investment, the post-tax rate of return on investment “s”, effective tax rates and the tax wedges as differences

• Prevention rates were obtained based on complementary homici

  2018-10-23

  

  Prevention rates were obtained based on complementary homicide rates, other thefts and vehicle theft rates weighted by the population. If we consider , as the highest homicide rate among the Federation units in a nevertheless t and as the homicide rate standard deviation, then the homicide prevent

• br Author Contributions br Conflict of

  2018-10-23

  

  Author Contributions Conflict of Interest Acknowledgments and Role of the Funding Source This work was supported in part by the Chinese National Key Basic Research Project 973 Grant 2013CB966800, the Mega-projects of Science Research for the 12th Five-Year Plan (2013ZX09303302), the State K

• br Material and Methods br Results br

  2018-10-23

  

  Material and Methods Results Discussion We document the expression of EBV viral miRNAs by three independent methods, small RNA sequencing, qRT-PCR and miRNA-ISH in malignant B cells, plasma and bone marrow biopsies of patients with CLL. It is noteworthy that more than 90% of adults older th

• prostaglandin receptors Our recent study comparing clinical

  2018-10-23

  

  Our recent study comparing clinical parameters and K+ transport in red prostaglandin receptors from HbSS and HbSC patients indicated significant differences between the two genotypes (Rees et al., 2015). In particular, KCC activity was higher in HbSC patients with more severe forms of SCD (Rees et a

• Beyond this fundamental research context independent studies

  2018-10-23

  

  Beyond this fundamental research context, independent studies confirmed an association of MSRV expression with MS (Perron et al., 2012; Sotgiu et al., 2010). Its envelope protein (MSRV-Env) was shown to elicit pro-inflammatory and autoimmune responses in immune mglur antagonist (Perron et al., 2001,

• br Children who experience early life seizures prolonged

  2018-10-23

  

  Children who experience early life seizures, prolonged febrile convulsions being the most common scenario, often have demonstrable problems with learning and memory later in life (). Although some of the children may go on to have epilepsy (recurrent unprovoked seizures) later in life, the problem

• We have demonstrated that a direct inhibitor

  2018-10-23

  

  We have demonstrated that a direct inhibitor on InhA can retain the outstanding profile of isoniazid and considering the DMPK parameters of both compounds the antitubercular effect is achieved at similar exposures of free drug proving our initial orexin antagonist and overcoming resistances mediate

• Previous studies have shown that remote IPC

  2018-10-23

  

  Previous studies have shown that remote IPC is involved in activation of multifactorial anti-inflammatory, neuronal, and humoral signaling pathways (Gassanov et al., 2014). For example, remote IPC could confer cardio-protection against ischemia through up-regulating erythropoietin (EPO) and hypoxia-

• Given this background the study of

  2018-10-23

  

  Given this background, the study of Scherer et al. reported in this issue () is of considerable interest, because it provides the first in-depth analysis of the change in the VLP/virion antibody repertoire in individual women who were naturally infected by HPV, and who are then vaccinated with VLPs.

• br Detection of cancer by analysis

  2018-10-23

  

  Detection of cancer by analysis of circulating cell-free DNA (cfDNA) has received enormous attention over the past years (). cfDNA is released into the blood circulation by apoptotic and necrotic cells, and cancer patients have increased concentrations of cfDNA (). With the development of novel te

• liothyronine sodium First are there characteristic sequentia

  2018-10-23

  

  First, are there characteristic sequential changes in liothyronine sodium related to the exacerbation of BD symptoms? So far, studies about the disturbances of circadian rhythms related to BD have been almost entirely cross-sectional (Nurnberger et al., 2000; Wood et al., 2009). If we identify seque

• In this issue of Castanho and colleagues address whether

  2018-10-23

  

  In this issue of Castanho and colleagues () address whether cognitive tests performed using videoconferencing could provide comparable diagnostic information as an in-clinic evaluation. They studied 69 individuals, aged 57 to 95years, across the diagnostic spectrum from normal to dementia and in va

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